Publications

Brooks SC, Fischer RL, Huh J H, Eichman BF.  2014.  5-methylcytosine recognition by Arabidopsis thaliana DNA glycosylases DEMETER and DML3. Biochemistry. 53(15):2525-32.

Mérai Z, Chumak N, García-Aguilar M, Hsieh T-F, Nishimura T, Schoft VK, Bindics J, Slusarz L, Arnoux S, Opravil S et al..  2014.  The AAA-ATPase molecular chaperone Cdc48/p97 disassembles sumoylated centromeres, decondenses heterochromatin, and activates ribosomal RNA genes. Proceedings of the National Academy of Sciences of the United States of America. 111(45):16166-71.

Ibarra CA, Feng X, Schoft VK, Hsieh T-F, Uzawa R, Rodrigues JA, Zemach A, Chumak N, Machlicova A, Nishimura T et al..  2012.  Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes. Science (New York, N.Y.). 337(6100):1360-4.

Lee H, Fischer RL, Goldberg RB, Harada JJ.  2003.  Arabidopsis LEAFY COTYLEDON1 represents a functionally specialized subunit of the CCAAT binding transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 100(4):2152-6.

Stone SL, Braybrook SA, Paula SL, Kwong LW, Meuser J, Pelletier J, Hsieh T-F, Fischer RL, Goldberg RB, Harada JJ.  2008.  Arabidopsis LEAFY COTYLEDON2 induces maturation traits and auxin activity: Implications for somatic embryogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105(8):3151-6.

Mosher RA, Tan E H, Shin J, Fischer RL, Pikaard CS, Baulcombe DC.  2011.  An atypical epigenetic mechanism affects uniparental expression of Pol IV-dependent siRNAs. PloS one. 6(10):e25756.

Hsieh T-F, Fischer RL.  2005.  Biology of chromatin dynamics. Annual review of plant biology. 56:327-51.

Huh J H, Bauer MJ, Hsieh T-F, Fischer RL.  2008.  Cellular programming of plant gene imprinting. Cell. 132(5):735-44.

Ohto M-aki, Fischer RL, Goldberg RB, Nakamura K, Harada JJ.  2005.  Control of seed mass by APETALA2. Proceedings of the National Academy of Sciences of the United States of America. 102(8):3123-8.

Choi Y, Gehring M, Johnson L, Hannon M, Harada JJ, Goldberg RB, Jacobsen SE, Fischer RL.  2002.  DEMETER, a DNA glycosylase domain protein, is required for endosperm gene imprinting and seed viability in arabidopsis. Cell. 110(1):33-42.

Gehring M, Huh J H, Hsieh T-F, Penterman J, Choi Y, Harada JJ, Goldberg RB, Fischer RL.  2006.  DEMETER DNA glycosylase establishes MEDEA polycomb gene self-imprinting by allele-specific demethylation. Cell. 124(3):495-506.

Penterman J, Zilberman D, Huh J H, Ballinger T, Henikoff S, Fischer RL.  2007.  DNA demethylation in the Arabidopsis genome. Proceedings of the National Academy of Sciences of the United States of America. 104(16):6752-7.

Xiao W, Custard KD, Brown RC, Lemmon BE, Harada JJ, Goldberg RB, Fischer RL.  2006.  DNA methylation is critical for Arabidopsis embryogenesis and seed viability. The Plant cell. 18(4):805-14.

Mok Y G, Uzawa R, Lee J, Weiner GM, Eichman BF, Fischer RL, Huh J H.  2010.  Domain structure of the DEMETER 5-methylcytosine DNA glycosylase. Proceedings of the National Academy of Sciences of the United States of America. 107(45):19225-30.

Yu A, Lepère G, Jay F, Wang J, Bapaume L, Wang Y, Abraham A-L, Penterman J, Fischer RL, Voinnet O et al..  2013.  Dynamics and biological relevance of DNA demethylation in Arabidopsis antibacterial defense. Proceedings of the National Academy of Sciences of the United States of America. 110(6):2389-94.

Jeong C W, Roh H, Dang T V, Choi Y D, Fischer RL, Lee J S, Choi Y.  2011.  An E3 ligase complex regulates SET-domain polycomb group protein activity in Arabidopsis thaliana. Proceedings of the National Academy of Sciences of the United States of America. 108(19):8036-41.

Ohto M-aki, Floyd SK, Fischer RL, Goldberg RB, Harada JJ.  2009.  Effects of APETALA2 on embryo, endosperm, and seed coat development determine seed size in Arabidopsis. Sexual plant reproduction. 22(4):277-89.

Hsieh T-F, Hakim O, Ohad N, Fischer RL.  2003.  From flour to flower: how Polycomb group proteins influence multiple aspects of plant development. Trends in plant science. 8(9):439-45.

Schoft VK, Chumak N, Choi Y, Hannon M, Garcia-Aguilar M, Machlicova A, Slusarz L, Mosiolek M, Park J-S, Park G T et al..  2011.  Function of the DEMETER DNA glycosylase in the Arabidopsis thaliana male gametophyte. Proceedings of the National Academy of Sciences of the United States of America. 108(19):8042-7.

Braybrook SA, Stone SL, Park S, Bui AQ, Le BH, Fischer RL, Goldberg RB, Harada JJ.  2006.  Genes directly regulated by LEAFY COTYLEDON2 provide insight into the control of embryo maturation and somatic embryogenesis. Proceedings of the National Academy of Sciences of the United States of America. 103(9):3468-73.

Penterman J, Uzawa R, Fischer RL.  2007.  Genetic interactions between DNA demethylation and methylation in Arabidopsis. Plant physiology. 145(4):1549-57.

Bauer MJ, Fischer RL.  2011.  Genome demethylation and imprinting in the endosperm. Current opinion in plant biology. 14(2):162-7.

Hsieh T-F, Ibarra CA, Silva P, Zemach A, Eshed-Williams L, Fischer RL, Zilberman D.  2009.  Genome-wide demethylation of Arabidopsis endosperm. Science (New York, N.Y.). 324(5933):1451-4.

Le BH, Cheng C, Bui AQ, Wagmaister JA, Henry KF, Pelletier J, Kwong L, Belmonte M, Kirkbride R, Horvath S et al..  2010.  Global analysis of gene activity during Arabidopsis seed development and identification of seed-specific transcription factors. Proceedings of the National Academy of Sciences of the United States of America. 107(18):8063-70.

Ohr H, Bui AQ, Le BH, Fischer RL, Choi Y.  2007.  Identification of putative Arabidopsis DEMETER target genes by GeneChip analysis. Biochemical and biophysical research communications. 364(4):856-60.

Rodrigues JA, Ruan R, Nishimura T, Sharma MK, Sharma R, Ronald PC, Fischer RL, Zilberman D.  2013.  Imprinted expression of genes and small RNA is associated with localized hypomethylation of the maternal genome in rice endosperm. Proceedings of the National Academy of Sciences of the United States of America. 110(19):7934-9.

Gehring M, Choi Y, Fischer RL.  2004.  Imprinting and seed development. The Plant cell. 16 Suppl:S203-13.

Xiao W, Gehring M, Choi Y, Margossian L, Pu H, Harada JJ, Goldberg RB, Pennell RI, Fischer RL.  2003.  Imprinting of the MEA Polycomb gene is controlled by antagonism between MET1 methyltransferase and DME glycosylase. Developmental cell. 5(6):891-901.

Choi Y, Harada JJ, Goldberg RB, Fischer RL.  2004.  An invariant aspartic acid in the DNA glycosylase domain of DEMETER is necessary for transcriptional activation of the imprinted MEDEA gene. Proceedings of the National Academy of Sciences of the United States of America. 101(19):7481-6.

Kirkbride RC, Fischer RL, Harada JJ.  2013.  LEAFY COTYLEDON1, a key regulator of seed development, is expressed in vegetative and sexual propagules of Selaginella moellendorffii. PloS one. 8(6):e67971.

Kwong RW, Bui AQ, Lee H, Kwong LW, Fischer RL, Goldberg RB, Harada JJ.  2003.  LEAFY COTYLEDON1-LIKE defines a class of regulators essential for embryo development. The Plant cell. 15(1):5-18.

Pedersen B, Hsieh T-F, Ibarra C, Fischer RL.  2011.  MethylCoder: software pipeline for bisulfite-treated sequences. Bioinformatics (Oxford, England). 27(17):2435-6.

Park G T, Frost JM, Park J-S, Kim T H, Lee J S, Oh S A, Twell D, Brooks J S, Fischer RL, Choi Y.  2014.  Nucleoporin MOS7/Nup88 is required for mitosis in gametogenesis and seed development in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America. 111(51):18393-8.

Kinoshita T, Miura A, Choi Y, Kinoshita Y, Cao X, Jacobsen SE, Fischer RL, Kakutani T.  2004.  One-way control of FWA imprinting in Arabidopsis endosperm by DNA methylation. Science (New York, N.Y.). 303(5657):521-3.

Apuya NR, Yadegari R, Fischer RL, Harada JJ, Goldberg RB, Harada JH.  2002.  RASPBERRY3 gene encodes a novel protein important for embryo development. Plant physiology. 129(2):691-705.

Hsieh T-F, Shin J, Uzawa R, Silva P, Cohen S, Bauer MJ, Hashimoto M, Kirkbride RC, Harada JJ, Zilberman D et al..  2011.  Regulation of imprinted gene expression in Arabidopsis endosperm. Proceedings of the National Academy of Sciences of the United States of America. 108(5):1755-62.

Xiao W, Brown RC, Lemmon BE, Harada JJ, Goldberg RB, Fischer RL.  2006.  Regulation of seed size by hypomethylation of maternal and paternal genomes. Plant physiology. 142(3):1160-8.

Dinneny JR, Yadegari R, Fischer RL, Yanofsky MF, Weigel D.  2004.  The role of JAGGED in shaping lateral organs. Development (Cambridge, England). 131(5):1101-10.

Franks RG, Liu Z, Fischer RL.  2006.  SEUSS and LEUNIG regulate cell proliferation, vascular development and organ polarity in Arabidopsis petals. Planta. 224(4):801-11.

Yamagishi K, Nagata N, Yee K M, Braybrook SA, Pelletier J, Fujioka S, Yoshida S, Fischer RL, Goldberg RB, Harada JJ.  2005.  TANMEI/EMB2757 encodes a WD repeat protein required for embryo development in Arabidopsis. Plant physiology. 139(1):163-73.

Kim M, Ohr H, Lee J W, Hyun Y, Fischer RL, Choi Y.  2008.  Temporal and spatial downregulation of Arabidopsis MET1 activity results in global DNA hypomethylation and developmental defects. Molecules and cells. 26(6):611-5.